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Updated: Jun 10, 2025

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
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Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes

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Prevention and potential remedies for antibiotic resistance: current research and future prospects

Rabiya Tabbassum Khan1, Vanshika Sharma1, Sofia Sharief Khan1

  • 1Molecular Biology Lab, School of Biotechnology, Shri Mata Vaishno Devi University, Katra, India.

Frontiers in Microbiology
|October 18, 2024
PubMed

Insights

Antibiotic resistance is a growing global threat, necessitating new drugs and improved antibiotic stewardship. Public awareness and innovative therapies like combinatorial treatments are crucial to combatting this crisis.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Pharmacology

Background:

  • Antibiotic resistance poses a significant global health threat, risking a return to the pre-antibiotic era.
  • The spread of resistance between bacterial strains necessitates urgent action to preserve antibiotic efficacy.
  • Effective strategies require both the development of new antibiotics and enhanced public awareness of appropriate use.

Purpose of the Study:

  • To review the current global status of antibiotic resistance.
  • To discuss methods for monitoring, preventing, inhibiting, and reversing bacterial resistance mechanisms.
  • To highlight the importance of public awareness and novel therapeutic approaches.

Main Methods:

  • Literature review of current research on antibiotic resistance.
  • Analysis of dissemination pathways of antibiotic-resistant organisms.
  • Exploration of strategies including novel antibiotic development, adjuvants, and combinatorial therapy.

Main Results:

  • Antibiotic resistance is escalating, with complex dissemination patterns.
  • New antibiotic analogs, adjuvants, and combinatorial therapies show promise.
  • Public awareness and responsible antibiotic use are critical for containment.

Conclusions:

  • Combating antibiotic resistance requires a multi-faceted approach.
  • Continued research into novel therapeutics and enhanced stewardship is essential.
  • Global collaboration and public education are vital to preserve antibiotic effectiveness.
Keywords:
antibiotic resistanceantibioticscombinational therapyglassmultidrug resistanceprevention strategies

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