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Updated: Jun 10, 2025

Large-scale Three-dimensional Imaging of Cellular Organization in the Mouse Neocortex
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Published on: September 5, 2018

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Cortical, striatal, and thalamic populations self-organize into a functionally connected circuit with long-term

Martina Brofiga1, Francesca Callegari2, Letizia Cerutti2

  • 1Department of Informatics, Bioengineering, Robotics, Systems Engineering (DIBRIS), University of Genova, Genova, Italy; ScreenNeuroPharm, Sanremo, Italy; Neurofacility, Istituto Italiano di Tecnologia (IIT), Genova, Italy.

Biosensors & Bioelectronics
|October 18, 2024
PubMed
Summary

Researchers created a brain circuit model to study neurological disorders. This engineered cortical-striatal-thalamic (CST) circuit shows self-organization and potential for learning and memory, offering insights into brain function and disease.

Keywords:
Brain-on-a-chipCortical neuronsMemoryMicroengineeringStriatal neuronsThalamic neurons

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