Effective cardiac disease classification using FS-XGB and GWO approach

Daphin Lilda S1, Jayaparvathy R1

  • 1Dept. of Electrical and Electronics Engineering, Sri Sivasubramaniya Nadar College of Engineering, Chennai, India.

PubMed

Insights

This study introduces a novel machine learning approach using grey wolf optimization for feature selection in electrocardiogram (ECG) analysis, significantly improving cardiovascular disease (CVD) detection accuracy with fewer features.

Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Artificial Intelligence

Background:

  • Cardiovascular diseases (CVDs) are a major global health concern, necessitating early detection.
  • Machine learning (ML) algorithms analyzing electrocardiogram (ECG) signals show promise for CVD prediction.
  • Effective ML models require significant feature extraction and selection from ECG data to enhance performance and reduce overfitting.

Purpose of the Study:

  • To develop an efficient ML model for identifying five types of CVDs using ECG features.
  • To employ Grey Wolf Optimization (GWO) for selecting a reduced, optimal feature set from ECG signals.
  • To evaluate a novel feature-specific extreme gradient boosting (FS-XGB) classifier against other ML methods.

Main Methods:

  • Extraction of pertinent features from ECG signals.
  • Application of Grey Wolf Optimization (GWO) for feature selection, reducing dimensionality.
  • Development and implementation of a feature-specific extreme gradient boosting (FS-XGB) classifier.
  • Comparative analysis of FS-XGB against Gradient Boosting, AdaBoost, Naïve Bayes, and SVM.

Main Results:

  • The proposed FS-XGB model achieved a maximum classification accuracy of 98.8% using only seven optimal features.
  • Exceptional performance metrics were recorded: 100% precision, 99.8% recall, 100% F1-score, and 98.8% AUC.
  • The methodology significantly outperformed existing approaches in terms of feature reduction and predictive accuracy.

Conclusions:

  • The GWO-based feature selection combined with FS-XGB offers a highly effective and efficient method for CVD detection from ECGs.
  • This approach demonstrates the potential for improved diagnostic tools in cardiology through advanced ML techniques.
  • The study highlights the importance of optimized feature selection for robust and accurate ML-based medical diagnoses.

Related Concept Videos

Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
1
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
1.5K
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
12.6K
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...