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Re: Deep Learning Artificial Intelligence Predicts Homologous Recombination Deficiency and Platinum Response from

Xuewei Wu1, Shuixing Zhang1, Bin Zhang1

  • 1Department of Radiology, First Affiliated Hospital of Jinan University, Guangzhou, China.

European Urology
|October 20, 2024
PubMed
Abstract

No abstract available in PubMed .

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The basic reaction of homologous recombination (HR) involves two chromatids that contain DNA sequences sharing a significant stretch of identity. One of these sequences uses a strand from another as a template to synthesize DNA in an enzyme-catalyzed reaction. The final product is a novel amalgamation of the two substrates. To ensure an accurate recombination of sequences, HR is restricted to the S and G2 phases of the cell cycle. At these stages, the DNA has been replicated already and the...