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Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
Published on: January 12, 2022
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Rheumatic diseases detected in patients presenting with uveitis
Esin Ozturk1, Tuba Yuce Inel2, Mahmut Kaya3
1Department of Internal Medicine, Dokuz Eylul University Faculty of Medicine, Izmir, Turkiye.
Northern Clinics of Istanbul
|October 21, 2024
Summary
Approximately one-third of patients with non-infectious uveitis were diagnosed with an underlying rheumatic disease. Early investigation for systemic inflammatory rheumatic diseases (IRD) is crucial for accurate diagnosis and treatment of uveitis.
Area of Science:
- Ophthalmology
- Rheumatology
- Internal Medicine
Background:
- Uveitis can be a presenting sign of systemic inflammatory rheumatic diseases (IRD).
- Identifying underlying IRD is critical for managing uveitis and preventing complications.
Purpose of the Study:
- To determine the incidence of IRD in patients initially presenting with non-infectious uveitis.
- To investigate the spectrum of rheumatic diseases associated with uveitis.
Main Methods:
- Adult patients with non-infectious uveitis were referred for rheumatologic evaluation.
- Demographic, clinical, laboratory, and imaging data were analyzed.
Main Results:
- 33% of 106 uveitis patients were diagnosed with an IRD.
- Spondyloarthritis (SpA) was common in anterior uveitis (20%); Behcet disease (BD) in panuveitis (27%) and posterior uveitis (33.3%).
- Posterior uveitis was often bilateral and recurrent.
Conclusions:
- Rheumatic diseases are a significant underlying cause of uveitis in approximately one-third of cases.
- Systemic workup for IRD is essential in uveitis patients for improved diagnosis and treatment outcomes.
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