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Updated: Jun 9, 2025

Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury
Published on: January 20, 2023
Sleep-Wake Disorders Among Older Adults Following Traumatic Brain Injury
Mira H Ghneim1, Meaghan Broderick2, Deborah M Stein2
1R Adams Cowley Shock Trauma, The University of Maryland School of Medicine, Baltimore, MD, USA. mira.ghneim@som.umaryland.edu.
Abstract:
Traumatic brain injuries (TBI) are increasingly common in older adults and represent a substantial source of morbidity and mortality for this population. In addition to the impact from the primary insult, TBI can lead to a variety of chronic neurocognitive conditions including dementia, depression, and sleep disturbances. When caused by TBI, these conditions differ importantly from their non-TBI-related counterparts. Much about how TBI relates to the development of these conditions is unknown, and more research is needed to further elucidate optimal treatment strategies.
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