Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Transbronchial biopsy during mechanical ventilation.

T A Papin, C M Grum, J G Weg

    Chest
    |February 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Venous thromboembolism: past, present and future.

    Seminars in respiratory and critical care medicine·2005
    Same author

    Educational interventions for asthma in children.

    The Cochrane database of systematic reviews·2003
    Same author

    Using a multimedia tool to improve cardiac auscultation knowledge and skills.

    Journal of general internal medicine·2001
    Same author

    Persistent respiratory irregularity in patients with panic disorder.

    Biological psychiatry·2001
    Same author

    Comparison of resident and medical student evaluation of faculty teaching.

    Evaluation & the health professions·2001
    Same author

    Antithrombotic therapy for venous thromboembolic disease.

    Chest·2001
    Same journal

    A Comparative Study of Radiation Exposure in Conventional and Robotic Bronchoscopy.

    Chest·2026
    Same journal

    Independent Prognostic Contributions of Anti-Ro52 and Anti-MDA5 in Autoimmune-Associated Interstitial Lung Disease.

    Chest·2026
    Same journal

    Lung aeration and gas exchange in SGA or AGA infants with moderate-severe BPD: secondary analysis of the PATH-BPD study.

    Chest·2026
    Same journal

    Lung Cancer Incidence and Mortality after Negative Low-Dose CT Screening Results.

    Chest·2026
    Same journal

    Symptom prevalence and impact on lung cancer risk in the SUMMIT study.

    Chest·2026
    Same journal

    How I Do It: De-escalation of Prostacyclin-Based Therapy in Patients Treated With Sotatercept.

    Chest·2026
    See all related articles

    Transbronchial biopsy (TBB) is a safe and valuable tool for diagnosing progressive pulmonary infiltrates in mechanically ventilated patients. This procedure provided crucial diagnostic data and altered treatment in several cases without significant adverse events.

    Area of Science:

    • Pulmonology
    • Critical Care Medicine

    Background:

    • Progressive pulmonary infiltrates in mechanically ventilated patients present diagnostic challenges.
    • Assessing the utility and safety of transbronchial biopsy (TBB) in this specific patient population is crucial.

    Purpose of the Study:

    • To evaluate the diagnostic yield and safety of transbronchial biopsy (TBB) in patients requiring mechanical ventilation for progressive pulmonary infiltrates.

    Main Methods:

    • Retrospective analysis of 15 mechanically ventilated patients who underwent TBB for progressive pulmonary infiltrates.
    • Assessment of diagnostic success, impact on therapeutic management, and complications.

    Main Results:

    • TBB yielded a diagnosis in 5 patients; bronchial secretions contributed to diagnosis in 2 more.

    Related Experiment Videos

  • Therapeutic management was significantly altered in 7 cases based on TBB results.
  • Transient, clinically insignificant changes in alveolar-arterial oxygen gradient and reversible hypercapnia were observed. Complications included bleeding and one pneumothorax; no fatalities occurred.

    • Conclusions:

    • Transbronchial biopsy is a safe procedure in hemodynamically stable, mechanically ventilated patients with diffuse lung disease.
    • TBB provides valuable diagnostic information that can significantly influence patient management.