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Indole ring binds to 7-methylguanine base by pi-pi stacking interaction. Crystal structure of 7-methylguanosine
FEBS Letters
|January 20, 1986
Abstract:
Strong pi-pi stacking interaction between the indole ring and 7-methylguanine base was shown by X-ray crystal analysis of the 7-methylguanosine 5'-monophosphate-tryptamine complex. This interaction appears to be strengthened by the attachment of ribose and phosphate groups to the base.