Relationship Between Electrical Parameters and Cardiac Synchrony in Patients Underwent Left Bundle Branch Area Pacing
Manxin Lin1, Shufen Huang1, Xinyi Huang2
1Division of Cardiology, Xiamen Cardiovascular Hospital, Xiamen University, Xiamen, Fujian, China.
Pacing and Clinical Electrophysiology : PACE
|October 22, 2024
Summary
Left bundle branch area pacing (LBBAP) can achieve optimal cardiac synchrony without requiring specific electrical parameters like LBB potential or a normal QRS axis. A stimulus to left ventricular activation time (Stim-LVAT) under 75 ms is suggested for ideal results.
Area of Science:
- Cardiology
- Electrophysiology
- Cardiac Pacing
Background:
- Left bundle branch area pacing (LBBAP) is an alternative pacing strategy.
- Assessing cardiac synchrony is crucial for optimizing pacing outcomes.
- Understanding the relationship between electrical and mechanical synchrony in LBBAP is important.
Purpose of the Study:
- To evaluate cardiac synchrony in patients undergoing LBBAP.
- To determine the correlation between electrical parameters and mechanical synchrony.
- To identify optimal electrical criteria for successful LBBAP and synchrony.
Main Methods:
- Eighty-two patients with successful LBBAP were analyzed.
- Electrical synchrony was measured by paced QRS duration (pQRSD) and Stim-LVAT.
- Mechanical synchrony was assessed using standard deviation of time-to-peak contraction velocity (Tsd-12-LV).
- Patients were subgrouped by LVAT, LBB potential, QRS axis, and PVI.
Main Results:
- No significant differences in electrical or mechanical synchrony were found among subgroups based on Stim-LVAT, LBB potential, PVI, or QRS axis.
- pQRSD and Tsd-12-LV did not show significant variations across the defined subgroups.
Conclusions:
- Specific electrical parameters (LBB potential, PVI, normal QRS axis) are not essential for effective LBBAP and optimal cardiac synchrony.
- A Stim-LVAT of < 75 ms may be a practical threshold for achieving ideal electrical and mechanical synchrony during LBBAP.
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