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Updated: Jun 9, 2025

Light-driven Enzymatic Decarboxylation
Published on: May 22, 2016
Light-Mediated Direct Decarboxylative Giese Aroylations without a Photocatalyst
David M Kitcatt1, Eva Pogacar1, Le Mi1
1Institute of Chemical Sciences, Heriot-Watt University, Edinburgh EH14 4AS, Scotland, United Kingdom.
Abstract:
Previous light-mediated approaches to the direct decarboxylative Giese aroylation reaction have mainly relied on the use of a photocatalyst and a reductive quenching pathway. By exploiting a mechanistically distinct oxidative protocol, we have successfully developed a photocatalyst-free, light-mediated direct Giese aroylation methodology.
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