[Women's particular pulmonary susceptibility to tobacco: the example of COPD]

THE EXAMPLE OF COPD . Women are more susceptible to the harmful effects of smoking than men, even with moderate exposure, and this vulnerability begins in childhood. The prevalence of smoking has even increased, in certain age groups of women, in France between 2019 and 2021. The consequences of smoking are chronic obstructive pulmonary disease (COPD), which develops earlier and more severely in women, even with mild exposure to tobacco, frequently leading to comorbidities such as osteoporosis and anxiety-depressive disorders. Several factors, mechanical, genetic, hormonal, and inflammatory, explain the vulnerability of the female lung to smoking. The management of smoking in women requires a gender-specific approach, including early detection of COPD and appropriate smoking cessation methods.