Socioeconomic costs of influenza complications in hospitalized children
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Updated: Jun 9, 2025

Rapid Molecular Detection and Differentiation of Influenza Viruses A and B
Published on: January 30, 2017
August Wrotek1,2, Malgorzata Czajkowska1,2, Edyta Zawlocka1,2
1Department of Pediatrics, Medical Center of Postgraduate Education, Warsaw, Poland.
Insights
Influenza complications in children significantly increase hospitalization costs. Infants under two years old incur the highest expenses, highlighting the need for targeted prevention strategies.
Area of Science:
- Pediatrics
- Public Health
- Health Economics
Background:
- Influenza is associated with numerous complications and substantial treatment costs.
- Estimating the socioeconomic impact of influenza hospitalizations is crucial for public health planning.
Purpose of the Study:
- To estimate the socioeconomic significance of influenza hospitalizations in children.
- To analyze the direct and indirect costs associated with pediatric influenza cases.
Main Methods:
- Retrospective analysis of 157 children hospitalized with influenza during the 2015-2016 season.
- Diagnosis confirmed via rapid influenza diagnostic test (RIDT) and/or polymerase chain reaction (PCR).
- Assessment of direct costs (treatment) and indirect costs (work absence, lost income).
Main Results:
- Complications occurred in 57.3% of hospitalized children, primarily pneumonia and bronchitis.
- Patients with complications had longer hospital stays (8 vs. 6 days) and higher total costs (€1042 vs. €779).
- Children under 2 years old incurred higher costs compared to older age groups.
Conclusions:
- Influenza complications lead to increased direct and indirect costs for patients and the healthcare system.
- Infants under two years old represent a particularly high-cost group for influenza-related hospitalizations.
Introduction:
Influenza may be correlated with a high number of complications and generate high costs of treatment. The study aimed to estimate the socioeconomic significance of hospitalized influenza cases.
Material And Methods:
In the 2015-2016 flu season 157 children (median age 17 months) were hospitalized in the Department of Pediatrics. The diagnosis was confirmed with the rapid influenza diagnostic test (RIDT), polymerase chain reaction (PCR) or both. The study assessed the direct and indirect costs of hospitalization, including the cost of treatment, work absence and the related income lost.
Results:
The frequency of complications among the children hospitalized was 57.3% (90/157), mainly due to pneumonia (31%) and bronchitis (23%). Patients with complications required longer hospital treatment (8 vs. 6 days, p < 0.01) and generated a higher total cost (€ 1042 vs. € 779, p < 0.01), including the patient's and systemic costs (€123 vs. € 94, p < 0.01 and € 916 vs. € 690, p < 0.01, respectively). Patients with complications had a 3.5-fold higher risk of generating higher (i.e., above median) costs. The difference in the costs between children aged under 2 and those over 2 years old was greater than the difference between children aged under 5 and those over 5 years old (€ 358 vs. € 253).
Conclusions:
Influenza complications generate higher systemic and patient's costs, both direct and indirect. The group of children for whom the difference is especially marked is under 2 years of age.
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