Related Experiment Video
Updated: Aug 1, 2026

Multiple Intravenous Bolus Dosing and Invasive Hemodynamic Assessment in a Hypoxia-Induced Mouse Pulmonary Artery Hypertension Model
Published on: November 11, 2022
Mitigating Intraoperative Hypotension: A Review and Update on Recent Advances
Wael Saasouh1, Navid Manafi2, Asifa Manzoor2
1Department of Anesthesiology, Wayne State University School of Medicine, 42 West Warren Avenue, Detroit, MI 48201, USA; NorthStar Anesthesia, 6255 State Highway 161 #200, Irving, TX 75038, USA; Outcomes Research Consortium, Cleveland, OH, USA.
Abstract:
Intraoperative hypotension (IOH) is a common occurrence during anesthesia administration for various surgical procedures and is linked to postoperative adverse outcomes. Factors contributing to IOH include hypovolemia, vasodilation, and impaired contractility, often combined with patient comorbidities. Strategies for mitigating IOH have been developed and are continually being updated with new research and technological advancements. These strategies include personalized blood pressure thresholds, pharmacologic measures, and the use of predictive tools. However, the management of IOH also requires careful consideration of patient-specific comorbidities and the use of appropriate treatment options.
Related Concept Videos
Antihypertensive Drugs: Vasodilators
Heart Failure Drugs: Diuretics
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
Parenteral Anesthetics: Overview
Cardiopulmonary Resuscitation IV: Pharmacological Management
Cardiomyopathy VII: Pre and Post Operative Nursing Management

