New-Onset Focal to Bilateral Tonic-Clonic Seizure Following COVID-19 Vaccination

Chun Seng Phua1,2, Azman Ali Raymond2, Shalini Bhaskar2

  • 1Monash University, Department of Neurosciences, Wellington Road, Clayton 3800, Victoria, Australia.

Insights

A young male experienced new-onset seizures shortly after his first COVID-19 vaccine dose. This case suggests COVID-19 vaccination may unmask an epilepsy predisposition, highlighting the need for further research.

Area of Science:

  • Neurology
  • Immunology
  • Vaccinology

Background:

  • Vaccinations are known to be associated with breakthrough seizures in susceptible individuals.
  • The neurological side effects of COVID-19 vaccines are still under investigation.
  • New-onset epilepsy following vaccination requires careful evaluation to determine potential triggers and underlying conditions.

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