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Cost-effectiveness Analysis Comparing Conventional and Digital Software Supported Management for Hypothyroidism
Jung Hyun Kim1, Jaeyong Shin2,3, Man S Kim4
1Division of Tourism and Wellness, Hankuk University of Foreign Studies (HUFS), Yongin 17035, Republic of Korea.
The Journal of Clinical Endocrinology and Metabolism
|October 24, 2024
Summary
Wearable digital monitoring for hypothyroidism is cost-effective, improving quality of life. This approach offers a favorable incremental cost-effectiveness ratio (ICER) compared to standard care.
Area of Science:
- Endocrinology
- Digital Health
- Health Economics
Background:
- Wearable devices can monitor thyroid function via heart rate correlation.
- Hypothyroidism management can be enhanced by digital monitoring solutions.
Purpose of the Study:
- To assess the cost-effectiveness of a wearable/mobile-based digital monitoring solution for hypothyroidism.
- Compare digital monitoring to conventional hypothyroidism management.
Main Methods:
- A Markov state-transition model simulated 10,000 patients with hypothyroidism.
- Evaluated cost-effectiveness from a healthcare perspective, using a 4.5% discount rate and 2022 cost adjustments.
- Calculated lifetime outcomes and incremental cost-effectiveness ratios (ICERs), with sensitivity analyses.
Main Results:
- The digital monitoring group gained 0.65 quality-adjusted life-years (QALYs) at an incremental cost of $11,700.87.
- The ICER was $17,988.97 per QALY gained, indicating cost-effectiveness.
- Digital monitoring was optimal in 99% of iterations against a willingness-to-pay threshold of $32,255/QALY.
Conclusions:
- Digital monitoring solutions are cost-effective for hypothyroidism management compared to standard care.
- The cost and sensitivity of the digital solution are critical for cost-effectiveness.
- Balancing digital monitoring costs, hormonal precision, and clinical effectiveness is essential.
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