Efficacy of Type III Thyroplasty in Vocal Masculinization in Trans Men: A Retrospective Observational Study

This observational study aims to evaluate the efficacy of type III thyroplasty (TP3) in achieving vocal masculinization in transgender men who have not obtained satisfactory results from testosterone therapy alone. Specifically, it aims to determine the change in the fundamental frequency (F0) of the voice before and after surgery and compare the results with previous studies.

A retrospective observational study.

Transgender men who were dissatisfied with their voice after at least 12months of testosterone therapy and underwent TP3 from January 2019 to January 2024 were evaluated. Acoustic voice analysis was performed before and 6months after surgery to measure changes in the fundamental frequency (F0) of the voice.

Thirteen transgender men, aged 20 to 54, were included. The mean preoperative F0 was 156 Hz, which significantly decreased to a mean postoperative F0 of 108.77 Hz, with a mean difference of 47.23 Hz (P-value <0.001). One patient developed subcutaneous emphysema postoperatively, which was managed successfully. No other significant complications were reported.

TP3 is an effective and safe surgical intervention for vocal masculinization in transgender men who do not achieve satisfactory results with testosterone therapy alone. This study, the largest series of TP3 cases in transgender men to date, underscores the importance and efficacy of this technique. Further research with larger sample sizes and longer follow-up periods is needed to confirm these findings and establish robust clinical protocols.