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Neoadjuvant combination immunotherapy in MSI/dMMR colorectal cancer

Meggy Suarez-Carmona1, Niels Halama2

  • 1Department of Cancer Immunology & Cancer Immunotherapy, German Cancer Research Center (DKFZ), Heidelberg, Germany; Helmholtz Institute for Translational Oncology (HI-TRON), Mainz, Germany.

Trends in Cancer
|October 24, 2024
PubMed
Abstract

Keywords:
MSIcolorectal cancerdMMRimmune checkpoint inhibitionneoadjuvant therapy

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Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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