Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

61
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
61
T Cell Types and Functions01:24

T Cell Types and Functions

955
When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
955

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Age-related histopathological and immunophenotypic variations in early-stage mycosis fungoides: a multicentre retrospective study in Türkiye.

BMJ open·2026
Same author

Factors Associated with Symptomatic Dermographism: Findings from the UCARE PREVALENCE-D Study.

American journal of clinical dermatology·2026
Same author

Clinical and Mycological Profiles of Chronic and Recalcitrant Dermatophytosis: Türkiye, 2022-2024.

Mycopathologia·2026
Same author

Real-World Predictors of Relapse-Free Duration After Narrowband UVB in Pediatric Psoriasis: A Multicenter Study.

Photodermatology, photoimmunology & photomedicine·2026
Same author

Hospital-Based Tap Water Iontophoresis for Primary Focal Hyperhidrosis: A Real-World Analysis of Treatment Adherence, Efficacy, and Relapse.

Journal of clinical medicine·2026
Same author

Herpes Zoster in Children in the Post-Vaccination Era: Age Shift, Clinical Characteristics, and Changing Dermatomal Patterns.

Vaccines·2026

Related Experiment Video

Updated: Jun 9, 2025

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
02:28

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Published on: March 1, 2024

339

Assessing systemic inflammatory markers in psoriasis: A retrospective study.

Berna Solak1, Rabia Öztaş Kara1

  • 1Department of Dermatology, School of Medicine, Sakarya University, Sakarya, Turkey.

Tropical Medicine & International Health : TM & IH
|October 25, 2024
PubMed
Summary
This summary is machine-generated.

Psoriasis patients exhibit elevated inflammatory markers like the systemic immune-inflammation index and neutrophil-to-lymphocyte ratio compared to healthy individuals. These markers correlate with disease severity, suggesting their utility in assessing psoriasis-related inflammation.

Keywords:
C‐reactive proteinmonocyte/high‐density lipoprotein cholesterol rationeutrophil‐to‐lymphocyte ratiopsoriasispsoriasis area and severity indexsystemic immune‐inflammation indexsystemic inflammation

More Related Videos

Accurate and Simple Measurement of the Pro-inflammatory Cytokine IL-1β using a Whole Blood Stimulation Assay
06:29

Accurate and Simple Measurement of the Pro-inflammatory Cytokine IL-1β using a Whole Blood Stimulation Assay

Published on: March 1, 2011

26.3K
Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response
12:50

Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response

Published on: September 15, 2017

6.5K

Related Experiment Videos

Last Updated: Jun 9, 2025

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
02:28

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Published on: March 1, 2024

339
Accurate and Simple Measurement of the Pro-inflammatory Cytokine IL-1β using a Whole Blood Stimulation Assay
06:29

Accurate and Simple Measurement of the Pro-inflammatory Cytokine IL-1β using a Whole Blood Stimulation Assay

Published on: March 1, 2011

26.3K
Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response
12:50

Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response

Published on: September 15, 2017

6.5K

Area of Science:

  • Dermatology
  • Immunology
  • Cardiovascular Health

Background:

  • Psoriasis is a chronic inflammatory skin condition.
  • It is frequently linked to cardiovascular diseases.
  • Systemic inflammation plays a key role in psoriasis pathogenesis.

Purpose of the Study:

  • To investigate the systemic inflammatory burden in psoriasis patients.
  • To identify inflammatory markers associated with psoriasis.
  • To assess the relationship between these markers and disease severity.

Main Methods:

  • Retrospective analysis of medical records from 2016-2022.
  • Inclusion of patients with psoriasis vulgaris and healthy controls.
  • Comparison of demographic data and various inflammatory markers including C-reactive protein, neutrophil-to-lymphocyte ratio, and systemic immune-inflammation index.

Main Results:

  • Psoriasis patients showed significantly higher levels of systemic immune-inflammation index, neutrophil-to-lymphocyte ratio, C-reactive protein, and other inflammatory markers compared to controls.
  • Severe psoriasis cases (Psoriasis Area and Severity Index >10) had higher levels of these markers than mild/moderate cases.
  • Several inflammatory markers, including systemic immune-inflammation index and neutrophil-to-lymphocyte ratio, demonstrated correlation with Psoriasis Area and Severity Index.

Conclusions:

  • Systemic immune-inflammation index, Systemic Inflammation Response Index, neutrophil-to-lymphocyte ratio, and C-reactive protein are potential simple and cost-effective markers.
  • These markers can aid in assessing the inflammatory burden in individuals with psoriasis.
  • Further research may validate their role in clinical practice for psoriasis management.