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Drug Regulation01:25

Drug Regulation

Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. Regrettably, the history of drug regulation is marred by several catastrophic events. One such incident is the Elixir Sulfanilamide tragedy, in which the toxic compound diethyl glycol was included in a sweet-tasting medication, leading to numerous fatalities. This event prompted the enactment of the Food, Drug, and Cosmetic Act in 1938. Under...
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Development and Performance Evaluation of a New Conformance Control Agent Gel.

Bin Ma1, He Wang1, Shu Jiang1

  • 1China University of Geosciences (Wuhan), Wuhan 430074, China.

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Summary

A novel supramolecular-polymer composite gel effectively plugs fractures in low-permeability oil reservoirs. This advanced gel enhances water flooding efficiency by forming a dual-network structure for superior plugging strength.

Keywords:
double networkinjection performancemulti-scale fracturesplugging strengthsupramolecular–polymer composite gel

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Area of Science:

  • Petroleum Engineering
  • Materials Science
  • Polymer Chemistry

Background:

  • Efficient water flooding in fractured low-permeability oil reservoirs is hindered by multi-scale fractured water channeling.
  • Effective plugging of these channels is crucial for optimizing oil recovery.

Purpose of the Study:

  • To develop a new supramolecular-polymer composite gel for plugging multi-scale fractured water channeling.
  • To evaluate the gel's performance as a conformance control agent in fractured low-permeability oilfields.

Main Methods:

  • Formulation of a composite gel using polyacrylamide, polyethyleneimine, cyclodextrin, and ethyl alcohol.
  • Characterization of the gelant's initial viscosity and injection performance in micro-fractures.
  • Analysis of the gel's double network structure formation at 40°C via covalent and self-assembly interactions.

Main Results:

  • The composite gelant exhibits low initial viscosity (<20 mPa·s) for effective injection into micro-fractures.
  • Upon gelation at 40°C, a stable double network structure is formed.
  • The resulting composite gel shows significantly enhanced strength (>5 × 10^4 mPa·s) and effective plugging in large-scale fractures.

Conclusions:

  • The developed supramolecular-polymer composite gel is a promising solution for plugging multi-scale fractured water channeling.
  • Its dual-network structure provides superior plugging performance in fractured low-permeability reservoirs.
  • The gel serves as an effective conformance control agent, improving water flooding efficiency.