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Related Concept Videos

Assessment of the Abdomen I: Inspection and Auscultation01:25

Assessment of the Abdomen I: Inspection and Auscultation

Introduction
The abdominal examination is a cornerstone of clinical medicine, serving as a critical tool in diagnosing various gastrointestinal (GI) diseases. It involves a systematic approach that includes inspection and auscultation, each with distinct yet complementary roles in assessing the abdomen. This article will delve into these two primary methods healthcare professionals use to examine the abdomen.
Inspection of the Abdomen
The first step in any abdominal examination is inspection.

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Engineered Vascularized Muscle Flap
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Hydrogel-Based Vascularized Organ Tissue Engineering: A Systematized Review on Abdominal Organs.

Filippos F Karageorgos1, Maria Alexiou1, Georgios Tsoulfas1

  • 1Department of Transplantation Surgery, Center for Research and Innovation in Solid Organ Transplantation, Aristotle University of Thessaloniki School of Medicine, 54642 Thessaloniki, Greece.

Gels (Basel, Switzerland)
|October 25, 2024
PubMed
Summary

This review explores hydrogel-based vascularized organ tissue engineering for abdominal organs like the liver and pancreas. While promising, challenges remain in creating fully functional, long-lasting engineered organs.

Keywords:
abdominal organsartificial intestineartificial kidneyartificial liverartificial organartificial pancreasbioprintinghydrogelstissue engineeringvascularized organ tissue engineering

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Area of Science:

  • Biomedical Engineering
  • Tissue Engineering
  • Regenerative Medicine

Background:

  • Tissue engineering offers alternatives to organ transplantation.
  • Applications include disease modeling and drug discovery.
  • Focus on generating functional organs and tissues.

Purpose of the Study:

  • Review hydrogel-based vascularized organ tissue engineering.
  • Focus on abdominal organs: liver, pancreas, kidneys, intestine, stomach, spleen.

Main Methods:

  • Comprehensive literature search of the Scopus database.
  • Included studies on hydrogel-based vascularized organ tissue engineering.
  • Latest search conducted on September 1, 2024.

Main Results:

  • 18 studies were included in the review.
  • Liver/hepatic tissue: 10 studies.
  • Pancreas/islet tissue: 5 studies.
  • Kidney/renal tissue: 3 studies.
  • Intestine/bowel tissue: 1 study.
  • Stomach/gastric tissue: 1 study.
  • Spleen tissue: 0 studies.

Conclusions:

  • Hydrogels serve as ideal, biocompatible scaffolds.
  • Organ tissue engineering is a rapidly advancing field.
  • Significant obstacles persist in creating fully functional, durable organs.