Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An Adaptive Cholic Acid Dimer for Selective Encapsulation.

International journal of molecular sciences·2026
Same author

Chitosan based hydrogels as temporary implants for breast cancer postsurgical treatment and site-infections prophylaxis.

International journal of biological macromolecules·2025
Same author

Quaternized Polysulfones as Matrix for the Development of Broad-Spectrum Antimicrobial Coatings for Medical Devices.

Polymers·2025
Same author

Thermally Solvent-Free Cross-Linked pH/Thermosensitive Hydrogels as Smart Drug Delivery Systems.

Gels (Basel, Switzerland)·2024
Same author

Chitosan-Electrospun Fibers Encapsulating Norfloxacin: The Impact on the Biochemical, Oxidative and Immunological Profile in a Rats Burn Model.

International journal of molecular sciences·2024
Same author

New Quaternary Ammonium Derivatives Based on Citrus Pectin.

Polymers·2024

Related Experiment Video

Updated: Jun 9, 2025

Fabrication of Size-Controlled and Emulsion-Free Chitosan-Genipin Microgels for Tissue Engineering Applications
05:26

Fabrication of Size-Controlled and Emulsion-Free Chitosan-Genipin Microgels for Tissue Engineering Applications

Published on: April 13, 2022

3.3K

Tuning Antioxidant Function through Dynamic Design of Chitosan-Based Hydrogels.

Manuela Maria Iftime1, Gabriela Liliana Ailiesei1, Daniela Ailincai1,2

  • 1"Petru Poni" Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley, 700487 Iasi, Romania.

Gels (Basel, Switzerland)
|October 25, 2024
PubMed
Summary
This summary is machine-generated.

New antioxidant chitosan hydrogels were created using dynamic imine bonds. These pH-responsive materials show promise for advanced biomedical applications.

Keywords:
antioxidant propertieschitosandynamic behaviorhydrogelsimine

More Related Videos

A Freeze-Thawing Method to Prepare Chitosan-Polyvinyl alcohol Hydrogels Without Crosslinking Agents and Diflunisal Release Studies
08:59

A Freeze-Thawing Method to Prepare Chitosan-Polyvinyl alcohol Hydrogels Without Crosslinking Agents and Diflunisal Release Studies

Published on: January 14, 2020

17.4K
Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture
08:05

Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture

Published on: September 29, 2017

19.1K

Related Experiment Videos

Last Updated: Jun 9, 2025

Fabrication of Size-Controlled and Emulsion-Free Chitosan-Genipin Microgels for Tissue Engineering Applications
05:26

Fabrication of Size-Controlled and Emulsion-Free Chitosan-Genipin Microgels for Tissue Engineering Applications

Published on: April 13, 2022

3.3K
A Freeze-Thawing Method to Prepare Chitosan-Polyvinyl alcohol Hydrogels Without Crosslinking Agents and Diflunisal Release Studies
08:59

A Freeze-Thawing Method to Prepare Chitosan-Polyvinyl alcohol Hydrogels Without Crosslinking Agents and Diflunisal Release Studies

Published on: January 14, 2020

17.4K
Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture
08:05

Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture

Published on: September 29, 2017

19.1K

Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Medicinal Chemistry

Background:

  • Chitosan is a biocompatible polysaccharide with potential in biomedical applications.
  • Developing functional chitosan-based materials with enhanced properties is crucial.
  • Dynamic covalent chemistry offers new strategies for material design.

Purpose of the Study:

  • To synthesize dynamic chitosan-based hydrogels with improved antioxidant properties.
  • To investigate the influence of reversible imine linkages on hydrogel characteristics.
  • To evaluate the potential of these hydrogels for biomedical applications.

Main Methods:

  • Hydrogel synthesis via reversible imine bond formation using 5-methoxy-salicylaldehyde.
  • Characterization using Scanning Electron Microscopy (SEM), Polarized Optical Microscopy (POM), and Nuclear Magnetic Resonance (NMR).
  • Assessment of swelling behavior, aldehyde release, and antioxidant activity (DPPH assay).

Main Results:

  • Successfully synthesized dynamic chitosan-based hydrogels with a porous structure.
  • Demonstrated pH-responsive swelling and controlled aldehyde release.
  • Achieved significantly enhanced antioxidant activity compared to unmodified chitosan.

Conclusions:

  • Dynamic imine linkages effectively create functional chitosan-based hydrogels.
  • These hydrogels possess tunable properties and superior antioxidant capacity.
  • The developed materials show significant potential for diverse biomedical applications.