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Author Spotlight: Exploring Cellular Zinc Regulation Through ZnT1 Functionality
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Published on: June 2, 2023

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NRF2 and Thioredoxin Reductase 1 as Modulators of Interactions between Zinc and Selenium

Alina Löser1,2, Maria Schwarz1,2, Anna Patricia Kipp1,2

  • 1Department of Nutritional Physiology, Institute of Nutritional Sciences, Friedrich Schiller University Jena, 07743 Jena, Germany.

Antioxidants (Basel, Switzerland)
|October 26, 2024
PubMed
Summary

Zinc influences selenium levels and activity of the selenoprotein thioredoxin reductase 1 (TXNRD1) by activating the NRF2 pathway. This explains the parallel decrease of selenium and zinc during inflammation.

Keywords:
NRF2seleniumselenium transporterthioredoxin reductasezinc

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