Related Experiment Video
Updated: Aug 4, 2026

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
Published on: October 17, 2013
Aphthoid ulcers in Crohn disease: radiographic course and relationship to bowel appearance
Abstract:
The relationship of aphthoid ulcers to the appearance of the colon in 14 patients with Crohn disease was determined by retrospective evaluation of radiographs obtained over several years during which various therapeutic regimens had been undertaken. The numbers and locations of the ulcers on the first radiographic examination were recorded and compared with the numbers and sizes on each subsequent examination. The appearance of the bowel area containing aphthoid ulcers was evaluated in comparison with ulcer-free areas. No attempt was made to correlate the course of ulceration with the therapeutic regimen. Results indicate that the fate of aphthoid ulcers is unpredictable. No significant correlation was found between changes in the appearance of the bowel and the numbers and locations of ulcers. Aphthoid ulcers can remain in the colon for years despite worsening or lessening of disease in other bowel segments. In some instances, the bowel segment containing ulcers became frankly diseased; in others, the ulcers disappeared and surrounding tissue appeared normal.
More Related Videos
07:38Multimodal Quantitative Phase Imaging with Digital Holographic Microscopy Accurately Assesses Intestinal Inflammation and Epithelial Wound Healing
Published on: September 13, 2016
05:50Gastric Point of Care Ultrasound in Adults: Image Acquisition and Interpretation
Published on: September 22, 2023
Related Concept Videos
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease I: Introduction
Inflammatory Bowel Disease III: Crohn's Disease
Inflammatory Bowel Disease IV: Clinical Manifestations