Overview of Antimicrobial Resistant ESKAPEE Pathogens in Food Sources and Their Implications from a One Health...

Area of Science:

• Microbiology
• Public Health
• Food Science

Background:

• Antimicrobial resistance (AMR) poses a significant global health challenge.
• ESKAPEE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Enterobacter species, and Escherichia coli) are major contributors to AMR.
• These pathogens are increasingly prevalent in healthcare and food production environments.

Purpose of the Study:

• To investigate the mechanisms of multidrug resistance in ESKAPEE pathogens.
• To analyze the occurrence of ESKAPEE pathogens in food and related reservoirs.
• To address challenges in controlling AMR spread within the food production chain.

Main Methods:

• Literature review of existing studies on ESKAPEE pathogens and AMR.
• Analysis of pathogen occurrence in food, water, and agricultural settings.
• Examination of surveillance programs for AMR monitoring.

Main Results:

• ESKAPEE pathogens exhibit diverse multidrug resistance mechanisms.
• These pathogens are found in various food products, water, and animal husbandry environments.
• Current surveillance often overlooks the food chain's role in AMR spread.

Conclusions:

• Understanding AMR in ESKAPEE pathogens requires a broader scope beyond healthcare.
• Effective control necessitates monitoring and intervention within the food production system.
• Public awareness campaigns are crucial for combating AMR in food-related sectors.