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The Potential Effects of Red Wine and Its Components on Neurocognitive Disorders: A Narrative Review
Virginia Boccardi1, Luca Tagliafico2,3, Angelica Persia2
1Division of Gerontology and Geriatrics, Department of Medicine and Surgery, University of Perugia, 06123 Perugia, Italy.
Nutrients
|October 26, 2024
Summary
Red wine polyphenols show promise for preventing cognitive decline in preclinical studies. However, current evidence is insufficient to recommend red wine for preventing neurocognitive disorders due to alcohol risks.
Area of Science:
- Neuroscience
- Gerontology
- Nutritional Science
Background:
- Aging populations face rising rates of chronic-degenerative diseases, especially neurocognitive disorders.
- Preventative strategies for these conditions are crucial.
- Red wine and its compounds show potential benefits for neurological conditions.
Purpose of the Study:
- To review current evidence on red wine's effects on neurocognitive disorders.
- To examine findings from both preclinical and clinical research.
Main Methods:
- Narrative review of existing scientific literature.
- Analysis of preclinical models and human clinical trials.
Main Results:
- Preclinical studies indicate red wine polyphenols may protect against dementia.
- Clinical evidence is inconclusive regarding the risk-benefit of alcohol for brain health.
Conclusions:
- Insufficient evidence supports red wine consumption for preventing neurocognitive disorders due to health risks.
- Polyphenols from red wine warrant further investigation for neuroprotective potential.
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