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Updated: Jun 9, 2025

Cecal Ligation Puncture Procedure
Published on: May 7, 2011
Association between albumin corrected anion gap and mortality in septic older adults
Qiang Zhou1, Yuxiu Miao2, Pengfei Wang3
1Department of Orthopedic Surgery, Hekou District People's Hospital, Dongying City, Shandong Province, China.
Objectives:
This study aimed to investigate the association between albumin corrected anion gap (ACAG) and 30-day mortality in septic older adults.
Methods:
In this study, multivariate Cox regression models and Kaplan-Meier analysis were employed to evaluate the correlation between ACAG and 30-day mortality in septic older adults.
Results:
After adjustment for potential confounders, each 1 mmol/L increase in ACAG was associated with a 6% increase in 30-day mortality (HR, 1.06 [1.03-1.08], P < 0.001). Higher levels of ACAG in septic older adults were associated with lower 30-day survival rates based on Kaplan-Meier analysis.
Conclusions:
This study observed a significant correlation between higher ACAG and 30-day mortality in septic older adults, thus indicating the need for increased attention from clinicians for patients with higher ACAG levels.
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