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Aminoglycoside antibiotics and sympathetic ganglionic transmission
Anaesthesia
|June 1, 1979
Abstract:
The effects of streptomycin, gentamicin, tobramycin and amikacin on transmission in sympathetic ganglia have been studied using the guinea pig isolated hypogastric nerve-vas deferens preparation. These aminoglycoside antibiotics produce dose-related sympathetic blockade at concentrations greater than the common therapeutically effective antibiotic concentrations.