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Uric Acid Levels in Overweight and Obese Children, and Their Correlation With Metabolic Risk Factors
Mohammed A AlAteeq1,2,3, Abdallh Almaneea4, Eyad K Althaqeb5
1Family Medicine Department, Ministry of National Guard - Health Affairs, Riyadh, SAU.
Cureus
|October 28, 2024
Summary
Over half of overweight or obese children and adolescents in Riyadh have hyperuricemia. Male gender and high LDL and TG levels increase this risk, highlighting the need for lifestyle interventions.
Area of Science:
- Pediatric Endocrinology
- Metabolic Disorders
- Public Health
Background:
- Obesity is a growing global health concern.
- Obesity is linked to metabolic disorders like type 2 diabetes, hyperlipidemia, and hyperuricemia.
- Understanding hyperuricemia prevalence in pediatric obesity is crucial for early intervention.
Purpose of the Study:
- To determine the prevalence of hyperuricemia in overweight and obese children and adolescents (6-14 years) in Riyadh, Saudi Arabia.
- To investigate the association between hyperuricemia and other metabolic factors in this population.
Main Methods:
- A cross-sectional study was conducted on 339 children and adolescents.
- Participants were randomly selected from patients seeking care for overweight/obesity at King Abdulaziz Medical City (KAMC), Riyadh.
- Data was collected via electronic medical records, including demographics, anthropometrics, serum uric acid, lipid profiles, and fasting blood sugar.
Main Results:
- The study included 339 participants: 14.2% overweight and 85.8% obese.
- The overall prevalence of hyperuricemia was 54%.
- Male gender, elevated LDL, and elevated triglycerides were associated with an increased risk of hyperuricemia.
Conclusions:
- Hyperuricemia is highly prevalent in overweight and obese children and adolescents.
- Promoting healthy lifestyles is essential for managing and controlling hyperuricemia in this vulnerable group.
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