Related Experiment Video
Updated: Jul 25, 2026
08:06
A Co-Culture Method to Study Neurite Outgrowth in Response to Dental Pulp Paracrine Signals
Published on: February 14, 2020
6.0K
Cervicofacial Necrotizing Fasciitis Originating From Odontogenic Infections: A Report of Two Cases
Hanan Wahbi1, Raqi Barber1, Sana Mando2
1Oral Pathology and Histology, Damascus University, Damascus, SYR.
Cureus
|October 28, 2024
Summary
Odontogenic infections can rarely lead to life-threatening cervicofacial necrotizing fasciitis (CNF). Early diagnosis and prompt surgical intervention with antibiotics are crucial for successful treatment of this severe condition.
Area of Science:
- Oral and Maxillofacial Surgery
- Infectious Diseases
Background:
- Cervicofacial necrotizing fasciitis (CNF) is a rare but severe soft tissue infection.
- Odontogenic infections are an infrequent but potential cause of CNF.
Observation:
- Two cases of CNF originating from odontogenic infections are presented.
- Case 1: A 33-year-old male with submandibular pain, skin necrosis, and gas infiltration, requiring skin grafting and reconstructive surgery.
- Case 2: A 14-year-old malnourished female with cervicofacial soft tissue necrosis, treated with antibiotics and surgery.
Findings:
- Odontogenic infections can precipitate severe, life-threatening conditions like CNF.
- Prompt diagnosis and aggressive management, including surgical debridement and intravenous antibiotics, are critical.
Implications:
- Highlights the severe potential consequences of seemingly minor dental infections.
- Emphasizes the importance of early clinical recognition and multidisciplinary treatment for CNF.
- Underscores the need for prompt surgical intervention and antibiotic therapy in managing odontogenic-related CNF.
Related Concept Videos
01:23Skin Diseases and Disorders
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
01:25Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
01:24Bacterial Meningitis
Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...
01:22Bacterial Meningitis I: Introduction
Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...