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Identification of the Novel HLA-DQB1*05:02:01:19 Allele in a Candidate Bone Marrow Donor by Next Generation

Diamanto Kouniaki1, Katerina Tarassi1, Alexandra Tsirogianni1

  • 1Immunology and Histocompatibility Department, Evangelismos General Hospital, Athens, Greece.

HLA
|October 28, 2024
PubMed

Keywords:
HLA‐DQB1*05:02:01:19 novel alleleIlluminanext generation sequencing

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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
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