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Updated: Jun 9, 2025

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Published on: September 11, 2021
The power of sample size calculations
Marieke S Jansen1, Rolf H H Groenwold1,2, Olaf M Dekkers1,3,4
1Department of Clinical Epidemiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Abstract:
Researchers frequently come across sample size calculations in the scientific literature they read, in projects undertaken by their peers, and likely within their own work. However, despite its ubiquity, calculating a sample size is often perceived as a hurdle and not fully understood. This paper provides a brief overview of sample size estimation to guide readers, researchers, and reviewers through its fundamentals.
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