Cephalic index and horizontal point of maximum width in children with normal brain development in China

Qinchuan Liang1, Zhipeng Shen2, Shouqin Sun1

  • 1Department of Neurosurgery, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, 1678 Dongfang Road, Shanghai, China.

BMC Pediatrics
|October 30, 2024
PubMed

Insights

This study establishes normal cephalic index (CI) and horizontal point of maximum width (H-PMW) ranges for Chinese children. These findings aid in diagnosing cranial deformities and assessing treatment effectiveness.

Area of Science:

  • Pediatric Radiology
  • Craniofacial Development
  • Medical Imaging

Background:

  • Establishing normative data for cephalic index (CI) and horizontal point of maximum width (H-PMW) is crucial for pediatric neurodevelopmental assessments.
  • Previous research has not comprehensively defined these parameters for healthy Chinese children.

Purpose of the Study:

  • To determine the normal range and distribution of the cephalic index (CI) and horizontal point of maximum width (H-PMW) in Chinese children.
  • To provide reference values for diagnosing cranial deformities in this population.

Main Methods:

  • Retrospective analysis of 456 Chinese Han children (0-15 years) with normal brain development.
  • Measurement of CI and H-PMW using thin-slice brain computed tomography (CT) images.
  • Data stratified by age groups and sex.

Main Results:

  • Overall mean CI was 86.6 ± 5.2; mean H-PMW was 53.7 ± 2.4.
  • CI peaked at 4-6 months (89.98) and was lowest at 2-3 years (84.31).
  • H-PMW was smallest at 4-6 months (52.17) and increased with age, reaching 54.88 by 8-15 years.

Conclusions:

  • The study provides essential reference ranges for CI and H-PMW in Chinese children.
  • These values are valuable for diagnosing cranial deformities.
  • The data supports assessing disease severity and treatment efficacy in pediatric patients.
Abstract