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Cephalic index and horizontal point of maximum width in children with normal brain development in China
Qinchuan Liang1, Zhipeng Shen2, Shouqin Sun1
1Department of Neurosurgery, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, 1678 Dongfang Road, Shanghai, China.
Insights
This study establishes normal cephalic index (CI) and horizontal point of maximum width (H-PMW) ranges for Chinese children. These findings aid in diagnosing cranial deformities and assessing treatment effectiveness.
Area of Science:
- Pediatric Radiology
- Craniofacial Development
- Medical Imaging
Background:
- Establishing normative data for cephalic index (CI) and horizontal point of maximum width (H-PMW) is crucial for pediatric neurodevelopmental assessments.
- Previous research has not comprehensively defined these parameters for healthy Chinese children.
Purpose of the Study:
- To determine the normal range and distribution of the cephalic index (CI) and horizontal point of maximum width (H-PMW) in Chinese children.
- To provide reference values for diagnosing cranial deformities in this population.
Main Methods:
- Retrospective analysis of 456 Chinese Han children (0-15 years) with normal brain development.
- Measurement of CI and H-PMW using thin-slice brain computed tomography (CT) images.
- Data stratified by age groups and sex.
Main Results:
- Overall mean CI was 86.6 ± 5.2; mean H-PMW was 53.7 ± 2.4.
- CI peaked at 4-6 months (89.98) and was lowest at 2-3 years (84.31).
- H-PMW was smallest at 4-6 months (52.17) and increased with age, reaching 54.88 by 8-15 years.
Conclusions:
- The study provides essential reference ranges for CI and H-PMW in Chinese children.
- These values are valuable for diagnosing cranial deformities.
- The data supports assessing disease severity and treatment efficacy in pediatric patients.
Background:
To identify the normal range and distribution in the cephalic index(CI) and horizontal point of maximum width(H-PMW) of Chinese children with normal brain development.
Methods:
We retrospectively analyzed Chinese Han children who visited our hospitals between June 2015 and June 2020 because of headache or suspected head injuries. 456 children (257 males, 199 females; aged 0-15 years) were enrolled and divided into 7 groups by age. The values of CI and H-PMW were measured using thin-slice brain computed tomography images.
Results:
The overall mean CI was 86.6 ± 5.2. The mean CI for males was 87.0 ± 5.1, and that for females was 86.0 ± 5.2. The overall mean H-PMW was 53.7 ± 2.4. The mean H-PMW for males was 53.8 ± 2.5, and that for females was 53.5 ± 2.3. The averages CI reached the maximum (89.98) at the age of 4-6 months, then began to decrease, decreased to the minimum (84.31) at the age of 2-3 years, and then gradually increased, and reached 86.17 at the age of 8-15 years. The average H-PMW was the smallest (52.17) at the age of 4-6 months, and reached 54.88 at the age of 8-15 years.
Conclusion:
The CI and H-PMW values of Chinese normal children reported in this study will provide a valuable reference to diagnose cranial deformities, assess the severity of the disease and the effectiveness of the treatment.
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