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Updated: Jun 9, 2025

Corneal Tissue Engineering: An In Vitro Model of the Stromal-nerve Interactions of the Human Cornea
Published on: January 24, 2018
A review of human cornea finite element modeling: geometry modeling, constitutive modeling, and outlooks
Guobao Pang1, Chenyan Wang2, Xiaojun Wang3
1Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, China.
Abstract:
The cornea is a vital tissue of the human body. The health status of the cornea has a great impact on the quality life of person. There has been a great deal of research on the human cornea biomechancis. However, the difficulty in obtaining the human cornea has greatly limited the research of cornea biomechancis. Using finite element modelling has become a very effective and economical means for studying mechanical properties of human cornea. In this review, the geometrical and constitutive models of the cornea are summarised and analysed, respectively. Some factors affecting of the finite element calculation are discussed. In addition, prospects and challenges for the finite element model of the human cornea are presented. This review will be helpful to researchers performing studies in the relevant fields of human cornea finite element analysis.
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