Examining Risk Factors Related to Cardiac Rehabilitation Cessation Among Patients With Advanced Heart Failure

Sharnendra K Sidhu1, Bernard S Kadosh, Ying Tang

  • 1Author Affiliations: Department of Medicine, New York University Grossman School of Medicine (Dr Sidhu); Leon H. Charney Division of Cardiology, New York University Grossman School of Medicine (Drs Kadosh, Katz, Reyentovich, and Dodson); and Department of Physical Medicine and Rehabilitation, New York University Grossman School of Medicine, New York, New York State (Drs Tang, Sweeney, Pierre, and Whiteson).

Insights

Nearly half of heart transplant and left ventricular assist device (LVAD) recipients completed cardiac rehabilitation (CR). Complete adherence to CR improved exercise capacity and outcomes in these patients.

Area of Science:

  • Cardiology
  • Rehabilitation Medicine

Background:

  • Cardiac rehabilitation (CR) is recognized for its benefits in patients who have undergone heart transplantation or received a left ventricular assist device (LVAD).
  • However, understanding the patterns of CR attendance and adherence in these specific patient populations remains limited.

Purpose of the Study:

  • To investigate the adherence rates and reasons for cessation of CR among heart transplant and LVAD recipients.
  • To compare post-operative complications, hospitalization duration, and readmissions between patients with complete and incomplete CR adherence.
  • To evaluate the impact of complete CR adherence on exercise parameters.

Main Methods:

  • A retrospective review was conducted on 137 heart transplant and LVAD recipients who participated in CR between 2013 and 2022.
  • Complete adherence was defined as attending 36 CR sessions.
  • Statistical analyses, including logistic and linear regressions, were used to compare outcomes between adherence groups, and paired sample t tests assessed changes in exercise metrics.

Main Results:

  • 91% of participants either completed 36 CR sessions or attended fewer than 24 sessions.
  • Among those not completing CR (n=74), medical reasons (72%) and personal reasons (15%) were primary cessation factors.
  • Incomplete adherence was associated with higher rates of post-operative complications (44% vs. 24%) and major bleeding (23% vs. 7%) prior to CR.
  • Complete adherence led to significant improvements in exercise time, metabolic equivalent of task (MET), and peak oxygen uptake.

Conclusions:

  • Approximately half of heart transplant and LVAD recipients achieved complete adherence to the 36-session CR protocol.
  • Complete adherence to CR is linked to significant improvements in exercise capacity and functional outcomes.
  • These findings highlight the crucial benefits of CR for heart transplant and LVAD recipients.
Abstract

Related Concept Videos

Heart Failure I: Introduction01:27

Heart Failure I: Introduction

Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
1
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
1.5K
Heart Failure V: Nursing Interventions01:30

Heart Failure V: Nursing Interventions

The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
1
Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
1
Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
1.3K
Heart Failure V: Medical Management01:30

Heart Failure V: Medical Management

Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
1