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Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...

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Updated: Jun 9, 2025

Visualization of DNA Compaction in Cyanobacteria by High-voltage Cryo-electron Tomography

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Quantitating Storage Granule Size, Accumulation, and Localization in Rhodobacter sphaeroides Using Cryo-Electron

Daniel Parrell^1,2,3, Rachelle A S Lemke^2,3, Joseph Olson¹

¹Department of Biochemistry, University of Wisconsin, Madison, WI, USA.

Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada

|October 31, 2024

Summary

No abstract available in PubMed .

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