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    Area of Science:

    • Global Health
    • Immunization Programs
    • Vaccine-Preventable Diseases

    Background:

    • The Immunization Agenda 2030 (IA2030) aims to reduce morbidity and mortality from vaccine-preventable diseases (VPDs).
    • The COVID-19 pandemic significantly disrupted global health systems and vaccination efforts.
    • Routine vaccination coverage has not yet returned to pre-pandemic levels.

    Purpose of the Study:

    • To present trends in routine vaccination coverage estimates through 2023.
    • To assess the impact of global events on vaccination goals.
    • To identify challenges in achieving equitable vaccination coverage.

    Main Methods:

    • Analysis of World Health Organization (WHO) and UNICEF routine vaccination coverage data.
    • Examination of data across 194 WHO member countries.
    • Focus on coverage of diphtheria-tetanus-pertussis-containing vaccine (DTPcv) and measles-containing vaccine (MCV).

    Main Results:

    • Global DTPcv and MCV first-dose coverage stagnated in 2022-2023, remaining below prepandemic levels.
    • Fragile, conflict-affected, and vulnerable (FCV) settings account for half of the world's unvaccinated children (14.5 million).
    • Introduction of new vaccines, like a second MCV dose in the African Region, has improved protection.

    Conclusions:

    • Urgent acceleration of routine and catch-up immunization programs is necessary.
    • Targeting unvaccinated children in FCV settings is critical for reducing VPDs.
    • Sustained efforts are needed to achieve IA2030 goals and prevent resurgence of VPDs.