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Updated: Jun 9, 2025

Solid-phase Synthesis of [4.4] Spirocyclic Oximes
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Synthesis of C-N or C-C Spiroindolines via Rearrangement Coupling Reaction

Xiaoling Liu1, Panpan Qiao1, Hui Chen1

  • 1Key Laboratory of Molecule Synthesis and Function Discovery, College of Chemistry, Fuzhou University, Fuzhou, Fujian 350116, China.

Organic Letters
|October 31, 2024
PubMed
Summary

A new rearrangement coupling reaction enables the synthesis of C-N and C-C spiroindolines from tetrahydro-β-carbolines. This efficient method offers operational simplicity and mild conditions for constructing complex molecules.

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