Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Structural Protein Function

Structural Protein Function

Structural proteins are a category of proteins responsible for functions ranging from cell shape and movement to providing support to major structures such as bones, cartilage, hair, and muscles. This group includes proteins such as collagen, actin, myosin, and keratin.
Collagen, the most abundant protein in mammals, is found throughout the body. In connective tissue, such as skin, ligaments, and tendons, it provides tensile strength and elasticity. In bones and teeth, it mineralizes to...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Neuroinflammation and Mental Health in Multiple Sclerosis and Autoimmune Encephalitis: Bridging Biological Mechanisms and Psychosocial Factors.

Archives of internal medicine research·2026

Same author

Most Effective Interventions for Enhancing Neural Plasticity for Functional Recovery in Patients with Traumatic Brain Injury.

Journal of surgery and research·2026

Same author

Post-Pandemic Evaluation of Emergency Medicine Workforce Stability.

Archives of clinical and medical case reports·2026

Same author

Mohs Surgery vs. Wide Local Excision for Non-Melanoma Skin Cancer: Comparing Recurrence Rates, Economic Value, and Aesthetic Outcomes.

Journal of cancer science and clinical therapeutics·2026

Same author

Cost-efficient and Accurate Risk Assessment Instruments in Type 2 Diabetics with Greatest Risk for Cardiovascular Disease.

Cardiology and cardiovascular medicine·2026

Same author

Shifting Career Landscapes: Analyzing the Fall in Physician-Owned Practices.

Archives of clinical and medical case reports·2026

Same journal

Genomics to Notebook (g2nb): Extending the Electronic Notebook to Address the Challenges of Bioinformatics Analysis.

Journal of bioinformatics and systems biology : Open access·2025

Same journal

CDC42 Regulatory Patterns Related To Inflammatory Bowel Disease and Hyperglycemia.

Journal of bioinformatics and systems biology : Open access·2025

Same journal

The Effects of Nitric Oxide on Choroidal Gene Expression.

Journal of bioinformatics and systems biology : Open access·2025

Same journal

Novornabreak: Local Assembly for Novel Splice Junction and Fusion Transcript Detection from RNA-Seq Data.

Journal of bioinformatics and systems biology : Open access·2024

Same journal

Transcriptional and Translational Regulation of Differentially Expressed Genes in Yucatan Miniswine Brain Tissues following Traumatic Brain Injury.

Journal of bioinformatics and systems biology : Open access·2024

Same journal

Linear Regression of Sampling Distributions of the Mean.

Journal of bioinformatics and systems biology : Open access·2024

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 8, 2025

Preparation of 3D Collagen Gels and Microchannels for the Study of 3D Interactions In Vivo

Preparation of 3D Collagen Gels and Microchannels for the Study of 3D Interactions In Vivo

Published on: May 9, 2016

Deciphering Collagen Phenotype Dynamics Regulators: Insights from In-Silico Analysis.

Resmi Rajalekshmi¹, Vikrant Rai¹, Devendra K Agrawal¹

¹Department of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California 91766 USA.

Journal of Bioinformatics and Systems Biology : Open Access

|November 1, 2024

Summary

This summary is machine-generated.

Understanding collagen (Col) I and III regulation is key for wound healing. This study analyzes factors controlling collagen expression, offering a framework for tissue regeneration therapies.

Keywords:

Bioinformatics Collagen I Collagen III Tissue regeneration Tissue repair Transcription factors Wound healing microRNA

More Related Videos

Generation of 3-D Collagen-based Hydrogels to Analyze Axonal Growth and Behavior During Nervous System Development

Generation of 3-D Collagen-based Hydrogels to Analyze Axonal Growth and Behavior During Nervous System Development

Published on: June 25, 2019

Imaging Denatured Collagen Strands In vivo and Ex vivo via Photo-triggered Hybridization of Caged Collagen Mimetic Peptides

Imaging Denatured Collagen Strands In vivo and Ex vivo via Photo-triggered Hybridization of Caged Collagen Mimetic Peptides

Published on: January 31, 2014

Related Experiment Videos

Last Updated: Jun 8, 2025

Preparation of 3D Collagen Gels and Microchannels for the Study of 3D Interactions In Vivo

Preparation of 3D Collagen Gels and Microchannels for the Study of 3D Interactions In Vivo

Published on: May 9, 2016

Generation of 3-D Collagen-based Hydrogels to Analyze Axonal Growth and Behavior During Nervous System Development

Generation of 3-D Collagen-based Hydrogels to Analyze Axonal Growth and Behavior During Nervous System Development

Published on: June 25, 2019

Imaging Denatured Collagen Strands In vivo and Ex vivo via Photo-triggered Hybridization of Caged Collagen Mimetic Peptides

Imaging Denatured Collagen Strands In vivo and Ex vivo via Photo-triggered Hybridization of Caged Collagen Mimetic Peptides

Published on: January 31, 2014

Area of Science:

Biochemistry
Molecular Biology
Regenerative Medicine

Background:

Collagen types I and III are crucial for wound healing and tissue regeneration.
Changes in collagen expression occur throughout wound healing stages.
Understanding collagen phenotype regulation is vital for tissue repair processes.

Purpose of the Study:

To comprehensively analyze factors regulating collagen (Col) I and III expression.
To elucidate the transcriptional and translational regulatory mechanisms of collagen synthesis.
To provide a foundational framework for therapeutic interventions in tissue regeneration.

Main Methods:

Critical analysis of published reports on collagen regulation.
Bioinformatics analysis of proinflammatory mediators, growth factors, elastases, and matrix metalloproteinases.
Network analysis to reveal interactions between genes, transcription factors, and microRNAs.

Main Results:

Identified key transcription factors and microRNAs involved in collagen expression regulation.
Revealed intricate interconnections within the regulatory landscape of collagen synthesis.
Established a holistic view of the complex regulatory network governing collagen expression.

Conclusions:

The study provides a comprehensive exploration of regulatory dynamics in collagen synthesis.
The findings lay the groundwork for future research and therapeutic strategies.
Modulating collagen expression can promote extracellular matrix remodeling and enhance tissue regeneration.