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Anti-Laminin γ1 and β4 Antibodies in Anti-p200 Pemphigoid

Hiroshi Koga1, Teruki Dainichi2, Takashi Hashimoto3

  • 1Department of Dermatology, Kurume University School of Medicine, Fukuoka, Japan; Institute of Cutaneous Cell Biology, Kurume University, Fukuoka, Japan.

The Journal of Investigative Dermatology
|November 3, 2024
PubMed
Abstract

No abstract available in PubMed .

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Laminins are heterotrimeric proteins with high molecular mass found in the extracellular matrix. Each laminin molecule is composed of three chains, viz. alpha, beta, and gamma, coded by five, four, and three paralogous genes, respectively. Laminins are categories based on the compositions of the three chains.
In humans, the five forms of alpha chains are LAMA 1, LAMA 2, LAMA 3, LAMA 4, and LAMA 5. The four forms of beta chains are LAMB 1, LAMB 2, LAMB 3, and LAMB 4. The three forms of gamma...

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