Benign intra- and extracranial meningioma

Area of Science:

• Neurology
• Neurosurgery
• Oncology

Background:

• Meningiomas are tumors arising from the meninges, the membranes surrounding the brain and spinal cord.
• While typically benign, meningiomas can exhibit multifocal growth patterns.
• Understanding the epidemiology and pathophysiology of these tumors is essential for clinical management.

Observation:

• This report details a rare case of multiple, nonmalignant meningiomas affecting both supratentorial and spinal locations of the cerebromedullary axis.
• The patient presented with changing neurological findings, necessitating a thorough diagnostic evaluation.

Findings:

• The case highlights the potential for benign meningiomas to manifest as multiple, distinct tumors.
• Review of existing literature supports the occurrence of multifocal intra- and extracranial meningiomas.
• Pathophysiological features of these multifocal tumors are discussed.

Implications:

• Clinicians should consider the possibility of multifocal benign meningiomas in postoperative patients presenting with new or evolving neurological deficits.
• This underscores the importance of comprehensive imaging and diagnostic workup in such scenarios.
• Awareness of this rare presentation can aid in timely and accurate diagnosis and management.