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Updated: Jun 8, 2025

Application of Hemostatic Devices in Laparoscopic Hepatectomy
Published on: April 19, 2022
Endoscopic Hemostasis and Antithrombotic Management
Jamie Bering1, Mashal J Batheja1, Neena S Abraham1
1Division of Gastroenterology and Hepatology, Mayo Clinic in Arizona, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA.
Insights
This review covers managing gastrointestinal bleeding (GIB) in patients taking antithrombotic medications. It details risks, benefits, and endoscopic hemostasis techniques for effective patient care.
Area of Science:
- Gastroenterology
- Hematology
- Internal Medicine
Background:
- Antithrombotic medications are crucial for preventing thrombotic events.
- Gastrointestinal bleeding (GIB) is a significant complication in patients using these drugs.
- Balancing antithrombotic therapy benefits against bleeding risks is essential.
Purpose of the Study:
- To review current literature on managing GIB in patients on antithrombotic therapy.
- To discuss risk assessment for both initial and recurrent GIB.
- To provide an overview of endoscopic hemostasis techniques for GIB.
Main Methods:
- Literature review of antithrombotic management and GIB.
- Analysis of risks associated with antithrombotic medications.
- Review of endoscopic hemostasis techniques.
Main Results:
- Antithrombotic therapy carries inherent bleeding risks, particularly GIB.
- Recurrent GIB is a significant concern requiring careful management.
- Various endoscopic techniques offer effective hemostasis for GIB.
Conclusions:
- Effective management of GIB in patients on antithrombotics requires a careful risk-benefit assessment.
- Endoscopic hemostasis techniques are vital for controlling GIB.
- Further research can optimize antithrombotic strategies and bleeding management.
Abstract:
This review highlights the available literature for antithrombotic management and hemostasis techniques that can be leveraged when caring for patients on antithrombotic medications who may develop gastrointestinal bleeding (GIB). Risks of both index GIB as well as risk of recurrent GIB are reviewed with emphasis on the balance between therapeutic benefits and bleeding hazards that are inherent with these medications. For management of these complications, an in-depth review of the various endoscopic hemostasis techniques that can be utilized is also provided.
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