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Author Spotlight: Advancements in Molecular Biomarker Testing for Non-Squamous Non-Small Cell Lung Cancer
Published on: September 8, 2023
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Patterns and Differences in Lung Cancer Treatment: United States, 2015-2020
Christine M Kava1, David A Siegel2, Jin Qin2
1Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA.
Chest
|November 4, 2024
Summary
Lung cancer treatment receipt varied by sociodemographics. Certain racial/ethnic groups and those in lower economic status counties received less treatment, highlighting disparities in cancer care.
Area of Science:
- Oncology
- Public Health
- Health Disparities
Background:
- Lung cancer survival rates remain low despite treatment advancements.
- Understanding treatment disparities is crucial for improving patient outcomes.
- Large-scale data analysis can reveal population-level trends in cancer care.
Purpose of the Study:
- To investigate how lung cancer treatment receipt differs based on sociodemographic characteristics in adults.
- To identify specific population subgroups experiencing disparities in cancer treatment.
Main Methods:
- Utilized 2015-2020 National Program of Cancer Registry data, covering 89% of the US population.
- Analyzed first-course treatment data for individuals aged 20+ diagnosed with lung and bronchus cancer.
- Employed multivariable logistic regression to assess associations between sociodemographics and treatment receipt.
Main Results:
- Among over 1 million lung cancer patients, 75% received at least one of four common treatments (surgery, chemotherapy, radiation, immunotherapy).
- Lower odds of receiving any treatment were observed in older adults (≥45 years), American Indian/Alaska Native, Black, and Hispanic individuals.
- Patients in nonmetropolitan counties, lower economic status areas, and the West census region also showed reduced treatment receipt.
Conclusions:
- Chemotherapy and radiation were the most frequent initial lung cancer treatments.
- Significant disparities in treatment access were identified among racial/ethnic minorities and socioeconomically disadvantaged populations.
- Further research is needed to understand and address the underlying factors contributing to these observed differences in cancer treatment.
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