Related Experiment Video
Updated: Jun 8, 2025
Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
Published on: January 12, 2022
Prognosis of patients with multiple sclerosis associated with uveitis
Marine Martin1, Jean-Sébastien Vidal2, Caroline Papeix1
1Department of Neurology Pitié-Salpêtrière Hospital, Sorbonne University, APHP-6, 47-83 Boulevard de l'hôpital, Paris, France.
Background:
Uveitis may be associated with multiple sclerosis (MS) in 1% of cases. Prognosis of this association remains unknown.
Methods:
We conducted a retrospective analysis in a cohort of 41 patients with MS (34 relapsing-remitting MS, and 7 secondary progressive MS) matched with 123 controls (MS without uveitis) followed in Department of Neurology, Pitié Salpêtrière Hospital, Paris.
Results:
Mean follow-up was 10.1 years (1.0-29.2). Disability accumulation measured as time to reach EDSS 3 was faster in patients with uveitis compared to the control group (p = 0.003) during follow-up.
Conclusions:
Our results suggest that uveitis may be associated with a worse MS prognosis.
