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Heliotropium bacciferum essential extraction: Compositions determination by GC-MS and anti-inflammatory and
Maha Hasni1, Nasser Belboukhari1, Khaled Sekkoum1
1Bioactive Molecule and Chiral Separation Laboratory, Faculty of Exact Sciences, University Tahri Mohamed of Bechar, PO Box 417, Bechar, 08000, Algeria.
Abstract:
Heliotropium bacciferum plant is very important and has been used for medicinal values since ancient times. The present study deals with the extraction of essential oil (0.14 w/w) of this plant and its GC-MS analysis, anti-inflammatory, and anti-bacterial activities evaluation. GC analysis of essential oil confirmed 76 compounds with 49 terpenes and oxygenated hydrocarbons. The main components of this essential oil are agarospirol (15.15 %), rosifoliol (9.41 %), elemol (8.96 %), tau.-cadinol (8.05 %), linalool (5.37 %), shyobunol (5.36 %) cyclohexylmethyl tridecyl ester of oxalic acid (4.74 %), respectively. The essential oil showed quite good anti-inflammatory activity while this oil indicated excellent anti-bacterial activity against 3 g-positive pathogenic bacteria (Bacillus subtilusATCC 6633, Entrococcus faecalis ATCC 29212, and Bacillus cereusATCC 11778). The essential oil of Heliotropium bacciferum showed great potential as an anti-inflammatory and anti-bacterial agent. Therefore, the reported extraction and GC-MS analysis methods are useful to extract the essential oil and determine the composition of other plants. The extracted essential oil may be used to treat several diseases.
