Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

2.5K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.5K
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

508
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
508
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

872
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
872
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

3.6K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
3.6K
Diabetes: Management and Pharmacotherapy01:15

Diabetes: Management and Pharmacotherapy

236
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
236

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Analysis of the Influence of Sex in 507 Patients With Moderate-to-Severe Atopic Dermatitis: Spanish Atopic Dermatitis Registry (BIOBADATOP).

Actas dermo-sifiliograficas·2026
Same author

Narrative Review on Perioperative Management in Dermatologic Surgery.

Actas dermo-sifiliograficas·2026
Same author

Bruton's Tyrosine Kinase (BTK) Inhibitors: A New Therapeutic Frontier in Dermatology.

Actas dermo-sifiliograficas·2026
Same author

[Hand eczema: comprehensive management and therapeutic perspectives in primary care].

Semergen·2026
Same author

Tralokinumab Effectiveness in Moderate-to-severe Atopic Dermatitis With Palmoplantar Eczema.

Actas dermo-sifiliograficas·2025
Same author

[Translated article] Violaceous Nodule on the Right Antehelix.

Actas dermo-sifiliograficas·2025

Related Experiment Video

Updated: Jun 8, 2025

Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers
04:09

Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers

Published on: March 3, 2023

2.8K

Medical Devices in Patients With Diabetes and Contact Dermatitis.

J P Velasco-Amador1, Á Prados-Carmona1, F J Navarro-Triviño2

  • 1Servicio de Dermatología. Hospital Universitario San Cecilio, Granada, Spain.

Actas Dermo-Sifiliograficas
|November 4, 2024
PubMed
Summary

Contact dermatitis from diabetes devices is rising. Isobornyl acrylate (IBOA) and other adhesive ingredients are key allergens, necessitating dermatologist involvement and manufacturer collaboration.

Keywords:
AllergensDiabetes mellitusGlucose sensorInsulin pumpsMedical devicesPatch testsSensitizationalérgenosbombas de insulinadiabetes mellitusdispositivos medicospruebas epicutáneassensibilizaciónsensor de glucosa

More Related Videos

Protocol to Create Chronic Wounds in Diabetic Mice
06:55

Protocol to Create Chronic Wounds in Diabetic Mice

Published on: September 25, 2019

20.1K
A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes
05:18

A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes

Published on: February 17, 2023

3.7K

Related Experiment Videos

Last Updated: Jun 8, 2025

Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers
04:09

Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers

Published on: March 3, 2023

2.8K
Protocol to Create Chronic Wounds in Diabetic Mice
06:55

Protocol to Create Chronic Wounds in Diabetic Mice

Published on: September 25, 2019

20.1K
A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes
05:18

A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes

Published on: February 17, 2023

3.7K

Area of Science:

  • Allergy and Dermatology
  • Biomedical Engineering
  • Endocrinology

Background:

  • Diabetes management revolutionized by glucose sensors and insulin pumps.
  • Increasing reports of contact dermatitis linked to these essential medical devices.
  • Identification of sensitizing allergens in device adhesives is a growing concern.

Purpose of the Study:

  • To identify allergens causing contact dermatitis in users of continuous glucose sensors and insulin pumps.
  • To highlight the prevalence and impact of allergic reactions to device components.
  • To inform dermatologists and endocrinologists about current and emerging allergens.

Main Methods:

  • Review of clinical cases and scientific literature on device-related contact dermatitis.
  • Identification of specific chemical compounds implicated as allergens.
  • Analysis of common and novel ingredients in current diabetes technology.

Main Results:

  • Isobornyl acrylate (IBOA) identified as a primary allergen in FreeStyle glucose sensors, leading to its removal.
  • Colophony, abietic acid derivatives, dipropylene glycol diacrylate, N,N-dimethylacrylamide, and triethylene glycol methacrylate are also implicated allergens.
  • Some identified allergens remain in use in widely available devices, posing ongoing risks.

Conclusions:

  • Allergic contact dermatitis to diabetes device components can significantly impact patient quality of life and treatment adherence.
  • Dermatologists are crucial in managing these reactions, guiding patient care, and collaborating with manufacturers.
  • Further research and clinical testing are needed for newly identified allergens to ensure patient safety and device efficacy.