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Updated: Jun 8, 2025

Electrochemical Preparation of Poly3,4-Ethylenedioxythiophene Layers on Gold Microelectrodes for Uric Acid-Sensing Applications
Published on: July 28, 2021
Electrochemical determination of Roxarsone using preconcentration-based signal amplification on modified
Luís M C Ferreira1, Paulo R Martins2, Cristiane G Silva2
1Center of Nature Sciences, Federal University of São Carlos, Rod. Lauri Simões de Barros km 12, 18290-000 Buri, SP, Brazil; Laboratory of Electrochemical Sensors (LabSensE) - Department of Chemistry, Federal University of Paraná, 81.531-980, Curitiba, PR, Brazil.
Abstract:
A lab-made screen-printed electrode based on poly(ethylene terephthalate) (PET) substrate modified with a hybrid film containing gold nanoparticles-decorated graphene (AuNPs-GRA/PET-SPE) was employed for the voltammetric determination of Roxarsone (ROX) in chicken purge and river water samples. The electrode exhibited an increased electroactive area and enhanced charge transfer due to the nanostructured matrix. The electrochemical determination involved a preconcentration approach with a reduction step of ROX at a constant potential of -0.6 V, followed by voltammetric sweep towards the oxidation of the adsorbed hydroxylamine at 0.32 V. The methodology achieved a limit of detection of 60 nM and 97 nM for ROX in diluted river water and chicken purge samples, respectively. This effective methodology offers a promising tool for monitoring ROX levels in environmental and food samples.
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