Related Experiment Video
Updated: May 4, 2026

17:15
Catheterization of Intestinal Loops in Ruminants
Published on: June 11, 2009
13.1K
Effect of toxin A and B of Clostridium difficile on rabbit ileum and colon
Gut
|January 1, 1986
Abstract:
The effect of purified toxin A and partially purified toxin B on rabbit ileum and colon was investigated. Toxin A caused tissue damage which was followed by permeability changes and fluid accumulation in both tissues. Toxin A did not increase the permeability of the colon to the extent observed for ileum; secreted fluid contained less protein of plasma origin. Toxin B had no effect on either tissue. Secretory and tissue damaging properties of crude C difficile toxins were found to be due to toxin A.

