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Published on: February 15, 2022
Risk factors for recovery from oculomotor nerve palsy after aneurysm surgery: a meta-analysis
Yuan Li1, Ming Zhao1, Xuemei Li1
1The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Background:
Risk factors for recovery from oculomotor nerve palsy (ONP) after aneurysm surgery explored by meta-analysis.
Methods:
The PubMed, Embase, web of science, Cochrane library, China Knowledge, Wan fang, and VIP databases were searched for case-control or cohort studies on risk factors of oculomotor nerve palsy recovery after aneurysm surgery, with a cut-off date of 14 February 2024, and data were analyzed using Stata 15.
Result:
A total of 12 articles involving 866 individuals were included, meta-analysis results suggesting that gender (OR = 0.75, 95% CI [0.51-1.10]), age (OR = 1.00, 95% CI [0.93-1.07]), aneurysm size (OR = 0.85, 95% CI [-0.71 to 1.01]), treatment time (OR = 1.01, 95% CI [0.91-1.13]) is not a risk factor for recovery of motor nerve palsy after aneurysm surgery. Preoperative complete ONP (OR = 2.27, 95% CI [1.07-4.81]), surgery (OR = 9.88, 95% CI [2.53-38.57]), subarachnoid hemorrhage (OR = 1.29, 95% CI [1.06-1.56]) is a risk factor for recovery of motor nerve palsy after aneurysm surgery.
Conclusion:
Based on the results of the studies we included, we found that complete ONP before surgery led to poorer recovery, but patients with post-operative and subarachnoid hemorrhage had better recovery.
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