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Updated: Jun 8, 2025

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
Sickle cell disease in India: Not just a mild condition
Manpreet Kochhar1,2, Patrick T McGann1,2
1Division of Pediatric Hematology/Oncology, Department of Pediatrics, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Abstract:
Sickle cell disease (SCD) is a common and life-threatening global health problem, with more than 500 000 affected infants born annually. The burden of SCD in sub-Saharan Africa is well established, but the comparably high prevalence in India is not well recognized and many consider SCD in India to be less severe. In their paper, a national study in India demonstrated the significant impact of SCD for patients, families and the healthcare system, supporting a call to action to recognize and address SCD as a serious and common health condition in India. Commentary on: Seth et al. Burden of vaso-occlusive crisis, its management, and impact on quality of life of Indian sickle cell disease patients. Br J Haematol 2025; 206:296-309.
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