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Updated: Jun 8, 2025

A New Method for Inducing a Depression-Like Behavior in Rats

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

The relationship between BMI and depression: a cross-sectional study.

Hongyu Cui¹, Ying Xiong², Chengmin Wang³

¹Department of Psychiatry, the First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.

Frontiers in Psychiatry

|November 6, 2024

Summary

This summary is machine-generated.

Maintaining a normal body mass index (BMI) is crucial for mental health. Both underweight and obesity are linked to increased depression risk, highlighting the importance of weight management for overall well-being.

Keywords:

body mass index depression relationship restricted cubic spline risk factor subgroup analysis

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Area of Science:

Public Health
Mental Health Research
Epidemiology

Background:

Depressive symptoms represent a growing public health concern.
The association between body mass index (BMI) and mental health, specifically depressive symptoms, remains unclear.

Purpose of the Study:

To investigate the relationship between body mass index (BMI) and depressive symptoms in adults.

Main Methods:

A multi-stage sampling method was employed, including 10,686 adults from Longgang District, Shenzhen.
Data collected via surveys in 2020-2021 included demographic and health information.
Statistical analyses included binary logistic regression, restricted cubic spline regression, and subgroup analyses.

Main Results:

A U-shaped relationship was observed between BMI and depression.
Both obesity and underweight were associated with an increased risk of depression.
This association was particularly pronounced in younger, highly educated, single, and employed individuals.

Conclusions:

Maintaining a normal body weight is recommended for depression prevention.
Weight management is essential for preserving both physical and mental health.
Further research may explore targeted interventions for at-risk subgroups.